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FAQs

Frequently Asked Questions

Considering GLP-1 treatment as part of your recovery?
Find answers to common questions below. If you don’t see what you’re looking for, we’re here to help by phone or email.

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What is a GLP-1 medication?

GLP-1 (glucagon-like peptide-1) medications are a class of drugs originally developed to treat type 2 diabetes and obesity. Common examples include semaglutide (Ozempic®, Wegovy®) and tirzepatide (Mounjaro®, Zepbound®). These medications work on areas of the brain involved in appetite, reward, satiation, and impulse control.  

How can a GLP-1 help with substance use cravings? 

Research suggests GLP-1 medications may reduce cravings by affecting the brain’s reward pathways, which are involved in both eating behaviors and substance use. Many patients report fewer urges to use alcohol, nicotine, or other substances while taking these medications.  

Does it work for alcohol cravings? Drug cravings? Both?

Early studies suggest GLP-1 medications may help reduce cravings and use of alcohol, nicotine, opioids, cocaine, and potentially other substances. The strongest evidence currently exists for alcohol use disorder, with emerging research in tobacco, opioids, stimulants, and other addictive behaviors. Usage of GLP-1s has also been proven to reduce nicotine cessation associated weight gain.  

Are GLP-1s FDA-approved for addiction treatment?

No. GLP-1 medications are not currently FDA-approved specifically for substance use disorders. However, a growing body of research—including clinical trials and observational studies—suggests they may be helpful as part of a comprehensive treatment plan. 

We also have a private pay option, billed at an affordable monthly rate. Our private pay option does not require a yearlong commitment. Our admissions staff will work closely with you on a month-to-month basis if this payment option is feasible for you.

Will it replace my current medication?

Usually not. GLP-1 medications are generally considered an adjunctive treatment, meaning they are added to—not substituted for—evidence-based treatments such as counseling, behavioral therapies, buprenorphine, naltrexone, or other prescribed medications. 

Will it make me lose weight? 

Weight loss is a common effect of GLP-1 medications. However, the amount varies significantly between individuals. Some patients lose substantial weight, while others experience only modest changes.  

What if I don't want to lose weight?

This is an important discussion to have with your provider. Treatment decisions are individualized, and potential benefits for cravings and recovery must be weighed against the possibility of weight loss.  

Will I be eligible if I'm already thin? 

Possibly. Eligibility depends on multiple factors, including your medical history, current weight, nutritional status, substance use history, and overall treatment goals. Being thin does not automatically exclude you, but additional considerations may apply.  

Is a certain BMI required? 

Yes. In order to initiate and remain on a GLP-1 medication, patients must maintain a BMI that is within healthy limits .

Why are there BMI requirements? 

Because GLP-1 medications commonly cause weight loss, we want to ensure that any weight loss remains within a healthy and safe range. BMI requirements help identify patients who are most likely to benefit from treatment while minimizing the risk of excessive weight loss, malnutrition, or other unintended health consequences.   

Are there any side effects? 

Common side effects include: 

  • Nausea  
  • Vomiting  
  • Diarrhea  
  • Constipation  
  • Stomach discomfort  
  • Reduced appetite  

 

Most side effects are mild and improve over time. Serious side effects are uncommon but can occur and should be discussed with your provider.  

How long would I take them? 

The optimal duration for addiction treatment is still being studied. Many patients remain on GLP-1 medications for months or years, depending on their response, treatment goals, and side effects.  

What happens if I stop taking them? 

Some patients experience a return of cravings, appetite, or other symptoms after discontinuation. Your provider can help determine whether tapering, maintenance treatment, or alternative therapies are appropriate.  

Is it covered by insurance?

Coverage varies widely by insurance plan. Some plans cover GLP-1 medications for diabetes or obesity, but most do not cover it for substance use disorders.   

How much does it cost?

Costs vary significantly depending on the medication, insurance coverage, and pharmacy. Without insurance coverage, monthly costs can range from several hundred to over one thousand dollars.  

Are GLP-1s safe? 

For most patients, GLP-1 medications are considered safe and well-tolerated when prescribed and monitored appropriately. As with any medication, risks and benefits should be reviewed with your healthcare provider.  

Is Aware using them because it's trendy? 

No. Aware Recovery Care’s interest in GLP-1 medications is based on emerging scientific evidence and their potential to improve recovery outcomes. Decisions regarding treatment are guided by research, patient safety, and individualized clinical care—not trends.

If cravings are reduced, does that improve outcomes? 

Often, yes. Cravings are one of the strongest predictors of recurrence. While reducing cravings does not guarantee recovery, lower craving levels are generally associated with improved treatment engagement, reduced substance use, improved overall health, and better long-term outcomes when combined with comprehensive addiction treatment.  

Where can I learn more about the science behind GLP-1 medications and addiction treatment?

We believe clients and healthcare providers should have access to the latest research. We’ve compiled a collection of published studies examining the use of GLP-1 medications for substance use disorder.

Read the research